The 2005 Gramatneusiedl (Austria) Train Collision. A passenger train's driver approaches a red signal too fast, causing him to crash into the side of a freight train. 43 people are injured.
The 1958 Newark Bay (NJ, USA) Train Derailment. A driver fails to obey red signals ahead of a movable bridge, causing his train to fall into the water. 48 people die. A link to the full story in the comments.
NTSB investigation has determined that 5/27/22 engine fire and over $1 million in damage to the OSV Ocean Guardian was caused by technicians installing a wrong size engine bearing.
January 13, 2012. The cruise ship Costa Concordia runs aground off the coast of Giglio in Italy. Here it is being salvaged on January 11, 2014, two years after it capsized.