During the filming of Raiders of the Lost Ark, Harrison Ford unintentionally uncovered what is believed to be a cursed artifact. By doing so, we have to suffer our worst nightmare, years of this detail being constantly reposted.
In Spider-Man: Into the Spider-Verse (2018), Miles asks "What's comic-con?" This is a reference to movie fans not being aware of comic-con this year since it won't have major movie studios showing up.